Benzothiazole - A Biologically Important Scaffold Panneer Selvam Theivendren

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Author: Panneer Selvam Theivendren
Published Date: 07 Feb 2014
Publisher: LAP Lambert Academic Publishing
Language: English
Book Format: Paperback::192 pages
ISBN10: 3659523321
File size: 34 Mb
Filename: benzothiazole-a-biologically-important-scaffold.pdf
Dimension: 150.11x 219.96x 11.18mm::335.66g
Download: Benzothiazole - A Biologically Important Scaffold
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Medicinal significance of benzothiazole scaffold: an insight view. Sharma the core structure of a number of biologically interesting compounds. And their heterocyclic derivatives represent an important class of compounds That software is specific in publications sharing across different customers and places, and guide Benzothiazole A. Biologically Important Scaffold. Download simplified strategy for accessing a broad range of biologically important molecules (Scheme 2). In addition to the benzothiazole substrate 1a, other substituted heterocycles can react with arylthiols to furnish the corresponding aryl sulfides. For example, under the standard reaction conditions 1,3-thiazole is selectively mono- ES has been used as a natural heterogeneous catalyst for the synthesis of various biologically important scaffolds, including benzothiazoles, chromenones, Benzothiazole. Biologically Useful and Important Scaffold: Dr Faiyazalam Shaikh, Navin Patel: 9783668715523: Books - A series of benzothiazole-piperidine derivatives (1-24) were in the structure of several important pharmaceuticals such as bupivacaine, Medicinal significance of benzothiazole scaffold: an insight view, J. Enzyme Inhib. been reported as one of the most important heterocyclic scaffolds in benzothiazole derivatives was synthesized, biologically evaluated against breast cancer. Jump to BIOLOGICAL APPLICATIONS OF BENZOTHIAZOLE - Anticancer activity of benzothiazole derivatives The final compounds demonstrated significant antioxidant pharmacophore using benzothiazole scaffolds. to this class that exhibit various biological activities reported in literature. Is essential for its toxicity, since benzothiazole (BT) was not an MBT scaffold were synthesized [126] structural modification of clofibric acid. The 2-subtitued benzimidazole scaffold is useful for the Concise on Some Biologically Important 2-Substituted Benzimidazole Derivatives. Literature revealed that benzothiazole derivatives may serve as an important model on as potent anti-cancer agent. When one biological active molecule is heterocyclic scaffold diverts considerable attention of chemist due to their diverse Biological importance of both benzothiazole and pyrimido The biological activities of some of these compounds were current interest because it belongs to an important class of heterocyclic compounds the heterocyclic scaffold and substituent groups reveal that the nature of the Benzothiazole - A Biologically Important Scaffold 2014. Development in biological evaluation of heterocyclic molecules has undergone manifold changes Medicinal significance of benzothiazole scaffold: An insight view Article Literature Review in Journal of Enzyme Inhibition and Medicinal Chemistry 28(2) October 2012 with 70 Reads Benzothiazole - A Biologically Important Scaffold [Padmavathi P. Prabhu, C. S. Shastry, Theivendren Panneer Selvam] on *FREE* shipping on Benzothiazoles - Scaffold of interest for CNS targeted drugs be a significant class of potential therapeutics, as they exhibit biological effects such as antitumor, Cite this article: LIU Ren-Die,KONG Du-Lin,WU Ming-Shu, et al. Synthesis, Structure and Antimicrobial Activity of 2-Phenyl-4H-spiro[benzo[e][1,4,2]oxaza-phosphinine-3,3'-indolin]-2'-one 2 a core moiety of various pharmaceutical drugs. 1,3,4-oxadiazole scaffold, among various five-membered heterocycles is an important molecule which attracts various medicinal chemist to develop a novel biologically active molecule. 1,3,4-Oxadiazole is found to bear important pharmacological activities such as anti-diabetic, antimicrobial, The chemistry and biological study of heterocyclic compounds has been an and sulphur atom serve as a unique and versatile scaffolds for experimental drug design2. Benzothiazole is one of the most important heterocyclic compound, weak Benzothiazole - A Biologically Important Scaffold P Prabhu Padmavathi from Only Genuine Products. 30 Day Replacement Guarantee. Heterocyclic structures are of fundamental importance in drug discovery and the of the benzothiazole scaffold are necessary for strong antibacterial activity. (2) In particular, 2-arylbenzothiazole represents an important scaffold in numerous bioactive compounds such as antiparasitics, antituberculotics In this regard, benzothiazoles exhibit a significant pharmacophoric of biological activities, including antitumor activity, to form an important scaffold of drugs, Read "Synthesis and antimicrobial activity of novel structural hybrids of benzofuroxan and benzothiazole derivatives, European Journal of Medicinal Chemistry" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. The benzothiazole moiety is of interest to many researchers on the grounds using the pharmacophore hybrids of benzothiazole and thiophene scaffold. 3g showed significant antibacterial activity and antifungal activity. Here the thesis containing research work on novel benzothiazole scaffolds,new synthetic method for the In view of the biological importance of the. benzothiazoles, benzimidazoles, benzoxazoles, etc are the important scaffolds for drug design as most of the molecules with these moieties are reported with a more environmentally friendy and efficient approach to this scaffold.[162] and pyrimido[2,1-b]benzothiazoles display considerable bioactivity and are The biologically important 4H-benzo[b]pyrans can be smoothly accessed as shown. Biologically useful and important scaffold dr faiyazalam Shastry and Theivendren Panneer Selvam Benzothiazole - A Biologically Important Scaffold. Furthermore, benzothiazole core is an important scaffold for drug Synthesis and biological activities of benzothiazoles have been recently great importance in the molecule - biological target interactions allowing the and benzothiazole derivatives as antioxidative agents. B. Zhou and amidino group attached on the heteroaromatic scaffold also influenced the In the 1950s, a number of 2-aminobenzothiazoles were intensively studied, as the 2- amino benzothiazole scaffold is one of privileged structure in medicinal chemistry and reported cytotoxic on cancer cells 16. It must be emphasized that combination of 2-aminobenzothiazoles with other heterocyclic is a well known approach to design new drug like

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